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Els suplements de vitamina D poden ajudar a prevenir les infeccions respiratòries

Els suplements de vitamina D poden ajudar a prevenir les infeccions respiratòries


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Els suplements de vitamina D s�associen a una lleugera reducci� del risc d�infecci� respirat�ria aguda, segons una metan�lisi (BMJ 2017;356:i6583), tot i que no es recomanaria en la majoria de persones, segons l�editorial acompanyant (BMJ 2017;356:j456).

L�administraci� de suplements de vitamina D �s motiu de forta controv�rsia, amb arguments a favor i en contra. En aquesta metan�lisi es van analitzar les dades individuals de 25 assaigs cl�nics controlats amb placebo de suplements de vitamina D2 o D3 en 11.000 pacients. La incid�ncia d�infecci� aguda de vies respirat�ries va ser inferior amb els suplements (40,3 %) que amb placebo (42.2 %). Els efectes beneficiosos es van limitar als participants que tenien uns nivells basals de 25-hidroxivitamina D de menys de 25 nmol/L, aix� com en els que no van rebre dosis en bolus. Els autors conclouen que els suplements de vitamina D s�n segurs i protegeixen de la infecci� respirat�ria aguda.

No obstant, els autors de l�editorial consideren que els resultats no s�n prou aplicables a la poblaci� general i que l�efecte cl�nicament rellevant continua sent incert, i per tant, probablement no s�hauria de canviar la pr�ctica cl�nica. Les dades actuals no donen suport a l��s de suplements de vitamina D per prevenir la malaltia, excepte en persones amb risc elevat d�osteomal�cia (amb nivells de 25-hidroxivitamina D de menys de 25 nmol/L).

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